Functional Modes of Proteins Are among the Most Robust

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Functional modes of proteins are among the most robust.

It is shown that a small subset of modes which are likely to be involved in protein functional motions of large amplitude can be determined by retaining the most robust normal modes obtained using different protein models. This result should prove helpful in the context of several applications proposed recently, like for solving difficult molecular replacement problems or for fitting atomic str...

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Functional modes of proteins are among the most robust ones

It is shown that a small subset of modes which are likely to be involved in protein functional motions of large amplitude can be determined by retaining the most robust normal modes obtained using different protein models. This result should prove helpful in the context of several applications proposed recently, like for solving difficult molecular replacement problems or for fitting atomic str...

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ژورنال

عنوان ژورنال: Physical Review Letters

سال: 2006

ISSN: 0031-9007,1079-7114

DOI: 10.1103/physrevlett.96.078104